The US State Department ordered non-emergency US government employees and the family members of US government personnel from US consulates in Lahore and Karachi to leave Pakistan due to "safety risks", the US embassy in Pakistan said in a statement.

Iran vowed to inflict a heavy price in retaliation. Drones struck adjacent the US consulate in Dubai, starting a fire but inflicting no casualties, and against the US military base at Al-Udeid in Qatar.

As the war against Iran launched by the United States and Israel rages on, pressure has been growing domestically for Indonesia to withdraw from the US-led Board of Peace, with Islamic communities and lawmakers questioning the body’s commitment to peace in the region.

Netanyahu rejected the idea of the conflict lasting years, like previous wars in the region.

The department, in posts on X, said it had updated travel advisories for Bahrain and Jordan "to reflect the ordered departure of non-emergency US government personnel and family members of government personnel."

In the aftermath, the US embassy issued shelter in place notifications for Jeddah, Riyadh and Dhahran and limited non-essential travel to any military installations in the region.

"We knew that there was going to be an Israeli action. We knew that that would precipitate an attack against American forces, and we knew that if we didn't preemptively go after them before they launched those attacks, we would suffer higher casualties," Rubio told reporters.

Shortly after the United States urged Americans to flee all Middle Eastern nations from Egypt eastward, smoke rose above the US embassy in Riyadh after it was hit by two drones, a Saudi defense spokesman said, although there were no immediate reports of injuries.

At least half a million Indonesians are stranded in the Middle East with limited options to escape, Indonesia’s Foreign Ministry confirmed on Monday, as the United States-Israeli war against Iran spread out across the region on its third day.

The shuttering will likely add to supply anxieties as shipping through the Strait of Hormuz, through which around a fifth of global oil consumption flows, grinds to a near-halt after vessels were attacked around it on Sunday.

One Chinese citizen was killed as a result of the conflict in Tehran, where Israel and the United States have been carrying out strikes in an operation that killed the Islamic republic's supreme leader.

The Israeli military said that "in response to Hezbollah's projectile fire "Israeli forces had "begun striking targets of the Hezbollah terrorist organization across Lebanon".

US and Israeli strikes - and Iranian retaliation - sent shockwaves worldwide through sectors from shipping to air travel to oil, amid warnings of rising energy costs and disruption to business in the Gulf region.

In the wake of the United States-Israeli war on Iran, markets are shaken and hundreds of thousands of Indonesians in the Middle East are left fearing an escalating war during the Islamic holy month of Ramadan.

"The Lincoln was not hit. The missiles launched didn’t even come close," US Central Command said on X.

Key transit airports including Dubai and Abu Dhabi in the UAE, and Doha in Qatar, were shut or severely restricted as much of the region’s airspace remained closed, with the Gulf grappling with uncertainty after US and Israeli strikes killed Iranian Supreme Leader Ayatollah Ali Khamenei on Saturday.

AFP reporters heard blasts in Dubai, Bahrain's capital Manama and Qatar -- where AFP correspondents saw thick black smoke rising on the clear morning horizon in the south of Doha. Shortly after, another wave of blasts reverberated through Dubai.

"Indonesia calls on all parties to exercise restraint and to prioritize dialogue and diplomacy," it said in a statement on X.

The strikes, which Trump said were aimed at destroying Iranian missiles and annihilating its navy, follow repeated US-Israeli warnings that they would strike Iran again if it pressed ahead with its nuclear and ballistic missile programs. 

Iran responded to the attack with a flurry of missile and drone strikes across the Middle East, killing at least one person in Abu Dhabi and another in Tel Aviv as explosions rocked the showcase cities of Gulf Arab monarchies.

Tehran emerged as one of Russia's closest allies during Moscow's Ukraine offensive and the Kremlin has been calling for restraint amid growing tensions and reports of a possible US intervention in Iran.

Iran launched missiles towards Israel, Israel's military said, and the Pentagon said the US strikes against Iran were named "OPERATION EPIC FURY." 

Explosions were heard in Tehran on Saturday, Iranian media reported, and sirens sounded across Israel around 8:15 a.m. local time in what the military said was a proactive alert to prepare the public for the possibility of an incoming missile strike.

Oman, which mediated the Geneva talks, offered a much rosier picture and said that Iran had agreed to zero stockpiling of any uranium, making moot the question of the level of enrichment.

President Prabowo Subianto has arrived in Abu Dhabi to bolster bilateral ties with the United Arab Emirates and advance Jakarta’s regional diplomacy, marking the fourth stop of his overseas tour during which Gaza has often emerged as a central issue.

The United States is the only permanent member of the United Nations Security Council to have joined the board. The other council members are Russia, China, Britain and France.

The US mission in Jerusalem said Tuesday that as part of an initiative to mark the 250th anniversary of US independence, it would provide Americans with "routine passport services in Efrat on Friday, February 27... for one day only".

Indonesia and Jordan pledged closer cooperation to address the escalating humanitarian crisis in Gaza and the West Bank during President Prabowo Subianto’s visit to Amman, following his attendance at the inaugural meeting of US President Donald Trump's Board of Peace meeting.

Modi, a Hindu nationalist, became the first prime minister in India's history to visit Israel in 2017, during which he and right-wing Prime Minister Benjamin Netanyahu took a barefoot stroll on a beach in the northern port city of Haifa. 

The Indonesian Embassy in Tehran has prepared contingency plans amid rising tensions between Iran and the United States, urging Indonesians to stay vigilant or to consider returning should conditions deteriorate.