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First iPS stem cell retina surgery

Japanese researchers Friday conducted the world’s firstsurgery with “iPS” stem cells on serious eye disease Friday, possibly pavingthe way for treatment of a common cause of blindness, two institutions involvedsaid

The Jakarta Post
Japan
Sat, September 13, 2014 Published on Sep. 13, 2014 Published on 2014-09-13T07:23:28+07:00

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First iPS stem cell retina surgery

J

apanese researchers Friday conducted the world'€™s firstsurgery with '€œiPS'€ stem cells on serious eye disease Friday, possibly pavingthe way for treatment of a common cause of blindness, two institutions involvedsaid.

A female patient with age-related macular degeneration (AMD), a common medical condition that can lead to blindness in older people, had a sheet of retina cells that had been created from iPS cells implanted.

The research team used induced Pluripotent Stem (iPS) cells -- which have the potential to develop into any cell in the body -- that had originally come from the skin of the patient, the institutions said in a statement.

Until the discovery of iPS several years ago, the only way to obtain stem cells was to harvest them from human embryos.

The surgery is still at an experimental stage, but if it is successful, doctors hope it will stop the deterioration in vision that comes with AMD.

The patient -- one of six expected to take part in the trial -- will be monitored over the next four years to determine how well the implants have performed, whether the body has accepted them and if they have become cancerous.

AMD, a condition that is incurable at present, affects mostly middle-aged and older people and can lead to blindness. It afflicts around 700,000 people in Japan alone.

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