The US is poised to indict Venezuelan President Nicolas Maduro and other key aides as the Trump administration ramps up pressure on an adversary it has sought to push aside, according to sources familiar with the decision.

The news comes as US Attorney General William Barr prepares to make an announcement at 11 a.m. EST.

President Donald Trump and top US officials have long sought to oust Maduro’s regime but have so far failed to replace him with the opposition leader they support, National Assembly President Juan Guaido. The charges, which were reported earlier by CNN and the Miami Herald, will be related to drug trafficking, the people said.

About $2 billion worth of cocaine, about a quarter of what’s produced in Colombia in a year, passes through Venezuela before making its way to other countries last year, according to Jeremy McDermott, co-founder of Insight Crime, a research group that studies organized crime.

There’s evidence that the criminal groups that transport these drugs have infiltrated Venezuelan government security forces, forming a network known as the ‘Cartel of the Suns’ to facilitate the passage of illicit drugs into and out the country, according to a 2019 report by the United Nations’ International Narcotics Control Board.

The indictment against Maduro, a sitting head of state, would be the first since the US issued charges against former Panamanian strongman Manuel Noriega. Noriega was eventually captured and sentenced to prison after then-President George H.W. Bush sent troops to the country to bring him to justice.