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End TB – Its time to tick the clock!

It is time to catapult the TB response on the fulcrum of technology throughout the TB cascade of care not only to maintain essential TB services, but also to improve TB case detection, adherence to treatment and treatment outcomes.

Ruma Bhargava (Mumbai, India)
Thu, March 25, 2021

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End TB – Its time to tick the clock! UN high-level meeting on TB targets (United Nations/-)

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reventable and treatable, yes TB is both. With this principle in line, the World Health Organization (WHO) announced the End TB Strategy in 2014 which aims to to reduce TB deaths by 95 percent and cutting the incidence by 90 percent between 2015 and 2035.

But, are we on the track to achieve the targets set forth?

The statistics speak otherwise. WHO reports that TB is amongst the top ten causes of death worldwide and the leading cause from infectious diseases. TB claimed and estimated 1.4 million lives in 2019, including 240, 000 amongst HIV positive persons. Across the globe, the incidence has fallen by 9 percent cumulatively between 2015-2019, which is less than half of the End TB Strategy milestone of 20 percent reduction between 2015 and 2020.

The Multi Drug resistant TB has emerged as a major health security threat, with a 10 percent increase in cases in 2019 from 2018.( https://www.who.int/news-room/fact-sheets/detail/tuberculosis). Presently, eight countries account for two thirds of the new TB cases with India taking the lead amongst Indonesia, China, Philippines, Pakistan, Nigeria, Bangladesh and South Africa.

Funding which is the main sword to fight TB saw half empty bags with less than 50 percent of the funding received for TB research, prevention, diagnosis, treatment and care as against the targets set. How can then we strengthen our fight when we know that low- and middle-income countries account for majority of the cases.

The COVID -19 pandemic, further threatens to reverse the progress made against the global burden. The Global TB report 2020, states that the economic impact of COVID could worsen two main determinants of cancer incidence, gross domestic product per capita and undernutrition.

Two modelling studies suggest that in the aftermath of COVID the progress made to control the disease could be reversed with the annual global TB deaths rising to the levels seen in 2015 or even 2012. The data further suggests that the number of people developing TB could increase by more than 1 million per year in the period 2020–2025.

As the perennial fangs of TB await to tighten their grip, it’s time to roll up our sleeves and face TB head on. Multisectoral collaborations clearly hold the imperative to lead the way forward. A mix of biomedical, public health and socioeconomic interventions combined with research and innovation will create a portfolio to tackle the menace.

However, with the constraints of funding, trained human resources and availability of infrastructure to conduct tests and support TB care and clinical decisions, mainly in low resource settings, technology or digital health is going to be torch bearer.

With 8.4 billion people having mobile phones and 47 percent internet coverage across the globe, Mobile Health (mHealth) and Electronic Health can be the real game changer and provide solutions and avenues for action on aspects of TB prevention, care and control. This can come as relief both for the patients in their quest for health and for the health professionals to carry out their work.

The Global Task Force on digital health for TB has identified 4 functions, namely patient care; surveillance and monitoring; programmatic management and eLearning wherein Information Communication Technology (ICT) can be tapped.

There have been remarkable examples across the globe to prove the success of digital health in each of the above four domains. In Kenya, cash transfers are being done through mobile banking to MDR-TB patients to support their treatment. In Swaziland, health managers can see maps of treatment facilities and infer how they relate to location of MDR-TB patients and treatment supporter’s home. QuanTB is a software-based program which creates a dashboard for drug forecasting and avoids drug stock outs.

Across the world, there are several other initiatives and resolves which are being taken to seize every opportunity that technology presents to empower people affected by TB and to strengthen the community and health systems, driving the response.

Keeping in view the importance of digital health, early this year The Stop TB Partnership hosted by UNOPS has launched a Digital Health Technology Hub (DHT Hub), a unifying virtual platform that brings together the organization’s expertise and work in the digital health technology space.

The World Economic Forum’s Centre for Fourth Industrial revolution, India under its Health Project – Fourth Industrial Revolution for Sustainable Transformation of Healthcare (FIRST) will also be working with a coalition of partners from government, academia, industry and civil society to conceptualize evidence based implementation and impact measurement frameworks to deploy emerging technologies like artificial intelligence, machine learning and blockchain in early detection, patient adherence and TB care in India.

It is time to catapult the TB response on the fulcrum of technology throughout the TB cascade of care not only to maintain essential TB services, but also to improve TB case detection, adherence to treatment and treatment outcomes.

The theme of World TB Day 2021 – “The clock is ticking” – conveys the sense that the world is running out of time to act on the commitments to end TB made by global leaders. The End TB strategy gave us a vison, we should now have a firm resolve to transform our commitments into actions.

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The writer is lead healthcare, the World Economic Forum.

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