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View all search results"Prior in vitro analyses and structural modeling regarding the individual mutations present in the Omicron variant indicate that there may be reduced neutralization activity of both vaccine-induced and monoclonal antibody-conveyed immunity, including the current REGEN-COV antibodies," the company said in a statement.
The company said on Friday that 75 percent of the participants in the trial for the therapy - two types of antibodies discovered by Vanderbilt University Medical Center - had chronic conditions including some with a lower immune response to vaccinations.
The findings by a Yokohama City University research team suggest that people who were infected in the early days of the pandemic, particularly those who had mild or no symptoms, still need to be vaccinated to reduce the risk of being infected by variants from Britain, South Africa, Brazil and India.
Preliminary findings by scientists at Public Health England (PHE) showed that reinfections in people who have COVID-19 antibodies from a past infection are rare - with only 44 cases found among 6,614 previously infected people in the study.
The findings from a study of 16 women released on Friday also found that most were mildly infected, while more severe reactions occurred in older women with a high body mass index - a trend that is mirrored in the general population.
Eli Lilly and Co on Wednesday said a single infusion of its experimental antibody treatment reduced the need for hospitalization and emergency room visits for clinical trial patients with moderate COVID-19.
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